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The active ingredient of Saizen ® is a human GH produced by recombinant DNA technology (r-hGH) with an amino acid sequence, structure, and pharmacokinetic profile identical to the dominant form of endogenous human GH. Pharmacokinetic parameters do not appear to differ between males and females, or between adults and children. 2Saizen® não deve ser usado em crianças nas quais ocorreu fusão epifisária. Contraindicações relativas Pacientes com Síndrome de Down, Síndrome de Bloom e Anemia de Fanconi não devem ser tratados com Saizen®. 5. ADVERTÊNCIAS E PRECAUÇÕES A idade óssea deve ser periodicamente determinada durante o tratamento com Saizen®,SAIZEN is a recombinant human growth hormone indicated for: Pediatric: Treatment of children with growth failure due to growth hormone deficiency (GHD) ( 1. 1) Adult: Treatment of adults with either adult onset or childhood onset GHD. ( 1. 2) Saizen Dosage and Administration320 295 Prescription required SKU: 824 Category: HGH Products Product ID: 824 Saizen is manufactured by EMD Serono, using recombinant DNA technology with a pharmacokinetic profile identical stricture to natural growth hormone. It comes with a reconstitution device, white powder and solvent solution in 5mg or 8. 8 mg vials. Saizen® is a brand of growth hormone made by EMD Serono Inc. . It is used to replace the growth hormone that is missing in a person's body. Saizen ® is currently FDA-approved for treating children or adults with growth hormone deficiency (GHD). Saizen ® is given as an injection. SAIZEN is a recombinant human growth hormone indicated for: Pediatric: Treatment of children with growth failure due to growth hormone deficiency (GHD) (1. 1) Adult: Treatment of adults with either adult onset or childhood onset GHD. 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