Brian Locke

History Research started to explain why WW2 pilots crashed at high altitude. Initially thought it was CO poisoning. e.g....

Acid removal: 30 - 60 mg of fixed acid is removed in kidney 14,000 mg of volatile acid is removed by the lungs VO2 (aka meta...

VA dataset CID 2019 DOI: 2020;71(5):1142–8 All patients 18+ screened with MRSA nasal swab at admission - 245,000 patients. ...

Consider how is it possible to be hypoxic without being hypoxemic? How is it possible to be hypoxemic without being hypoxic ...

Leadless pacemaker self contained generator and electrode that is implanted into the right ventricle for single chamber pacin...

https://doi.org/10.4187/respcare.09316 The mathematical model describing this is the Equation of Motion for th...

Reference: https://www.nejm.org/doi/full/10.1056/NEJMra1403503 Physiology generally, pleural pressure is below atmosphere....

Occupational lung disease: includes pneumoconioses HP bronchiolitis occupational asthma...

EPIC study: Viral PNA = 20-30% of CAP (https://www.cdc.gov/pneumonia/epic/publications.html) but not easily identifiable as a distinct...

TTE EF Assessment https://www.pocus101.com/assessing-left-ventricular-ejection-fraction-with-echocardiography/ Qualitative metho...

Technique spirometer should be calibrated daily with a 3L syringe. testing should be done on physiologic norm...

PVR = (mPAP - PCWP) / CO. (V=IR) rearranges to: mPAP = (PVR * CO) + PCWP <= increase each leads to mPAP (exercise, ...

Gases and Liquids are both fluids. Pressure = Force / Area = (Force x Distance) / (Area x Distance) = Work / Volume = Ener...

PROSEVA Protocol Proned for at least 16 hours per day if: P:F 150 or less with PEEP 10 or more and FiO2 60% or mo...

## CX Terms (Fleischner 1 based. Fleischner 2 is more focused on CT terms) Optical Density (aka the amount of blackening): factor of a...

GERD Source: JAMA. 2020;324(24):2536-2547. doi:10.1001/jama.2020.21360 Definition: recurrent trou...

CCM 2020 Review - https://journals.lww.com/ccmjournal/Fulltext/2019/05000/Renal_Replacement_Therapy_in_the_ICU.12.aspx...

Ventilatory Failure Work of breathing Not synonymous with respiratory rate Phasic contraction of sternocleinomastoid i...

Diagnosis and Detection CPG 2020: https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.202007-874CME

Analgesia, Amnesia, and NM blockade Sedatives Fentanyl analgosedation (monotherapy) - estimated to be su...